New Step by Step Map For Lorlatinib
Desk one summarizes the observed DLTs by cohort. Somnolence, which settled in all but one particular affected individual, was the only real DLT for MLN8054 given with out methylphenidate or modafinil. The onset of somnolence and its severity normally were correlated with dose and Cmax. Due to the fact somnolence was regarded as relevant to Cmax, th